There is an issue with Design Mode Lock. During computer startup (Mac OS), when opening MDP2 (v 2.3330), Design Mode is locked. Need to go to Config > Options to unlock. Then select Already Bought, and Unlock again. MDP2 should remember my purchase.
I believe this existed since MDP2 was available on M1 Macs.
Images
Design Mode locked 1
Design Mode locked 2